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Positive inotropic effects of carbon monoxide-releasing molecules (CO-RMs) in the isolated perfused rat heart

BACKGROUND AND PURPOSE: Carbon monoxide (CO) generated by the enzyme haeme oxygenase-1 (HO-1) during the breakdown of haeme is known to mediate a number of biological effects. Here, we investigated whether CO liberated from two water soluble carbon monoxide-releasing molecules (CO-RMs) exerts inotro...

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Bibliographic Details
Main Authors: Musameh, M D, Fuller, B J, Mann, B E, Green, C J, Motterlini, R
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014642/
https://ncbi.nlm.nih.gov/pubmed/17057755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706939
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