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Carbon monoxide-releasing molecules (CO-RMs) attenuate the inflammatory response elicited by lipopolysaccharide in RAW264.7 murine macrophages

1. The enzyme heme oxygenase-1 (HO-1) is a cytoprotective and anti-inflammatory protein that degrades heme to produce biliverdin/bilirubin, ferrous iron and carbon monoxide (CO). The anti-inflammatory properties of HO-1 are related to inhibition of adhesion molecule expression and reduction of oxida...

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Detalhes bibliográficos
Main Authors: Sawle, Philip, Foresti, Roberta, Mann, Brian E, Johnson, Tony R, Green, Colin J, Motterlini, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576195/
https://ncbi.nlm.nih.gov/pubmed/15880142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706241
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