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Human thiopurine methyltransferase activity varies with red blood cell age

AIMS: Inherited differences in thiopurine methyltransferase (TPMT) activity are an important factor in the wide interindividual variations observed in the clinical response to thiopurine chemotherapy. The aim of this study was to establish a population range for red blood cell (RBC) TPMT activity in...

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Autori principali: Lennard, L, Chew, T S, Lilleyman, J S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014613/
https://ncbi.nlm.nih.gov/pubmed/11736862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01497.x
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