Dihydroergotamine: discrepancy between arterial, arteriolar and pharmacokinetic data

AIMS: To investigate the peripheral vascular effects and pharmacokinetics of dihydroergotamine (DHE) 0.5 mg after a single subcutaneous administration in humans. METHODS: A double-blind, placebo-controlled cross-over study was performed in 10 healthy male subjects. A wash-out period of 2 weeks separ...

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Detalhes bibliográficos
Main Authors: de Hoon, J N J M, Poppe, K A, Thijssen, H H W, Struijker-Boudier, H A J, Van Bortel, L M A B
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Pharmacokinetics/Pharmacodynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014503/
https://ncbi.nlm.nih.gov/pubmed/11453889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01415.x
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