Oral bioavailability of dihydroartemisinin in Vietnamese volunteers and in patients with falciparum malaria

AIMS: To obtain comprehensive bioavailability data for artesunate (ARTS) and its active metabolite dihydroartemisinin (DHA) following their separate oral administration to Vietnamese volunteers and to patients with acute, uncomplicated falciparum malaria. METHODS: Volunteers were randomized to recei...

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Autori principali: Binh, Tran Quang, Ilett, Kenneth F, Batty, Kevin T, Davis, Timothy M E, Hung, Nguyen Canh, Powell, Shane M, Thu, Le Thi Anh, Van Thien, Huynh, Phuöng, Hoang Lan, Phuong, Vu Duong Bich
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2001
Soggetti:
Pharmacokinetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014487/
https://ncbi.nlm.nih.gov/pubmed/11422013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2001.01395.x
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