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Is cytochrome P450 2C9 genotype associated with NSAID gastric ulceration?

AIMS: The aim of this study was to explore whether genetic variation of cytochrome P450 2C9 (CYP2C9) contributes to NSAID-associated gastric ulceration. The hypothesis tested was that CYP2C9 poor metabolizer genotype would predict higher risk of gastric ulceration in patients on NSAIDs that are meta...

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Autors principals: Martin, Jennifer H, Begg, Evan J, Kennedy, Martin A, Roberts, Rebecca, Barclay, Murray L
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014482/
https://ncbi.nlm.nih.gov/pubmed/11422024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01398.x
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