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Pharmacokinetics and systemic β(2)-adrenoceptor-mediated responses to inhaled salbutamol

AIMS: To examine whether systemic β(2)-adrenoceptor responses, such as tachycardia, tremor and hypokalaemia, can be used as a surrogate for the 20 min pharmacokinetic profile of inhaled salbutamol. METHODS: A retrospective analysis of eight separate published studies in healthy volunteers was perfor...

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Dettagli Bibliografici
Autori principali: Fowler, Stephen J, Lipworth, Brian J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014458/
https://ncbi.nlm.nih.gov/pubmed/11318774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2001.01362.x
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