Comparison of the extrapulmonary beta2-adrenoceptor responses and pharmacokinetics of salbutamol given by standard metered dose-inhaler and modified actuator device.

1. Ten healthy subjects were randomised to inhale salbutamol via a standard metered-dose inhaler (MDI), or via a modified metered-dose actuator device (MA). Previously published radiolabelled aerosol data had shown that the MA device produced a lower aerosol velocity, reduced oropharyngeal depositio...

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Main Authors: Newnham, D M, McDevitt, D G, Lipworth, B J
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364617/
https://ncbi.nlm.nih.gov/pubmed/12959292
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