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Effect of α(1)-acid glycoprotein on the intracellular accumulation of the HIV protease inhibitors saquinavir, ritonavir and indinavir in vitro

AIMS: Since α(1)-acid glycoprotein (AGP) levels may be raised during HIV infection, we have examined in vitro the effect of increasing the concentration of AGP on the intracellular accumulation of the HIV protease inhibitors saquinavir (SQV), ritonavir (RTV) and indinavir (IDV). METHODS: U937 cells...

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Autores principales: Jones, K, Hoggard, P G, Khoo, S, Maher, B, Back, D J
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014422/
https://ncbi.nlm.nih.gov/pubmed/11167671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01324.x
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