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Effect of α(1)-acid glycoprotein on the intracellular accumulation of the HIV protease inhibitors saquinavir, ritonavir and indinavir in vitro

AIMS: Since α(1)-acid glycoprotein (AGP) levels may be raised during HIV infection, we have examined in vitro the effect of increasing the concentration of AGP on the intracellular accumulation of the HIV protease inhibitors saquinavir (SQV), ritonavir (RTV) and indinavir (IDV). METHODS: U937 cells...

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Autors principals: Jones, K, Hoggard, P G, Khoo, S, Maher, B, Back, D J
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014422/
https://ncbi.nlm.nih.gov/pubmed/11167671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01324.x
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