Possible enhancement of the first-pass metabolism of phenacetin by ingestion of grape juice in Chinese subjects

AIMS: This serendipitous study revealed an unexpected effect of Jufeng grape juice on the CYP1A2-mediated metabolism of phenacetin. Investigation of the inhibition of CYP1A2 by grapefruit juice was involved but a translation error led to the grape juice substitution. METHODS: Twelve healthy subjects...

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Detalhes bibliográficos
Main Authors: Xiao Dong, S, Zhi Ping, Z, Zhong Xiao, W, Chong Shu, C, Fattore, C, Gatti, G, D’Urso, S D, Perucca, E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014370/
https://ncbi.nlm.nih.gov/pubmed/10583039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00065.x
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