Possible enhancement of the first-pass metabolism of phenacetin by ingestion of grape juice in Chinese subjects

AIMS: This serendipitous study revealed an unexpected effect of Jufeng grape juice on the CYP1A2-mediated metabolism of phenacetin. Investigation of the inhibition of CYP1A2 by grapefruit juice was involved but a translation error led to the grape juice substitution. METHODS: Twelve healthy subjects...

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Bibliographische Detailangaben
Hauptverfasser: Xiao Dong, S, Zhi Ping, Z, Zhong Xiao, W, Chong Shu, C, Fattore, C, Gatti, G, D’Urso, S D, Perucca, E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 1999
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014370/
https://ncbi.nlm.nih.gov/pubmed/10583039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00065.x
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