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Platelet glycoprotein IIb/IIIa blockade with tirofiban: effect on aggregation caused by P256, an antibody to human IIb/IIIa receptors

AIMS: P256 is a divalent antibody which aggregates human platelets by interaction with glycoprotein (GP) IIb/IIIa receptors. We investigated the effect of tirofiban, an antagonist of the GP IIb/IIIa receptor, on P256-mediated platelet aggregation. METHODS: Responses to agonists were measured turbido...

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Détails bibliographiques
Auteurs principaux: Fisher, Ian, Robinson, Paul, Ritter, James M
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014294/
https://ncbi.nlm.nih.gov/pubmed/10417496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00990.x
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