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Integrated modelling of the clinical pharmacokinetics of SDZ HTF 919, a novel selective 5-HT(4)receptor agonist, following oral and intravenous administration

AIMS: The purpose of the present study was to assess the pharmacokinetics of the novel selective 5-HT(4) receptor agonist SDZ HTF 919 (HTF) including food effect, absolute bioavailability, interoccasion and intersubject variabilities. METHODS: In the randomized, open-label, three treatment, four per...

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Main Authors: Appel-Dingemanse, Silke, Lemarechal, Marie-Odile, Kumle, Anette, Hubert, Martine, Legangneux, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014177/
https://ncbi.nlm.nih.gov/pubmed/10336571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00936.x
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