Blockade of MCH1 receptor signalling ameliorates obesity and related hepatic steatosis in ovariectomized mice

BACKGROUND AND PURPOSE: Melanin-concentrating hormone (MCH) is a cyclic orexigenic neuropeptide predominantly expressed in the lateral hypothalamus. We investigated the roles of MCH1 receptor signalling in ovariectomy (OVX)-induced obesity in female C57BL/6J mice, an animal model of postmenopausal o...

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Autors principals: Gomori, A, Ishihara, A, Ito, M, Matsushita, H, Mashiko, S, Iwaasa, H, Matsuda, M, Bednarek, M A, Qian, S, MacNeil, D J, Kanatani, A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2007
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014135/
https://ncbi.nlm.nih.gov/pubmed/17519948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707292
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