Mechanism of the anti-obesity effects induced by a novel Melanin-concentrating hormone 1-receptor antagonist in mice

BACKGROUND AND PURPOSE: Melanin-concentrating hormone (MCH) is an orexigenic neuropeptide expressed in the lateral hypothalamus that is involved in feeding and body weight regulation. Intracerebroventricular infusion of a peptidic MCH1 receptor antagonist ameliorated obesity in murine models. Recent...

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Bibliographic Details
Main Authors: Ito, Masahiko, Ishihara, A, Gomori, A, Matsushita, H, Ito, Makoto, Metzger, JM, Marsh, DJ, Haga, Y, Iwaasa, H, Tokita, S, Takenaga, N, Sato, N, MacNeil, DJ, Moriya, M, Kanatani, A
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2010
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Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825359/
https://ncbi.nlm.nih.gov/pubmed/20015294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00536.x
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