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Role of neutrophil elastase in LTB(4)-induced neutrophil transmigration in vivo assessed with a specific inhibitor and neutrophil elastase deficient mice

BACKGROUND AND PURPOSE: The serine protease neutrophil elastase (NE) appears to regulate inflammatory responses at multiple levels but its role in leukocyte transmigration in vivo remains unclear. The present study aimed to address this issue by using both an NE inhibitor (ONO-5046) and NE deficient...

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Bibliografski detalji
Glavni autori: Young, R E, Voisin, M-B, Wang, S, Dangerfield, J, Nourshargh, S
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013993/
https://ncbi.nlm.nih.gov/pubmed/17471175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707267
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