GW3965, a synthetic liver X receptor (LXR) agonist, reduces angiotensin II-mediated pressor responses in Sprague–Dawley rats

BACKGROUND AND PURPOSE: Liver X receptors (LXRs) activate genes that regulate lipid and cholesterol metabolism. LXR agonists were shown recently to also increase murine renin gene expression in vivo. To further examine a link between lipid metabolism, the renin-angiotensin-aldosterone-system and blo...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Leik, C E, Carson, N L, Hennan, J K, Basso, M D, Liu, Q-Y, Crandall, D L, Nambi, P
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2007
Sujets:
Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013964/
https://ncbi.nlm.nih.gov/pubmed/17420776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707241
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