LXR activation by GW3965 alters fat tissue distribution and adipose tissue inflammation in ob/ob female mice

To investigate the role of liver X receptor (LXR) in adipose tissue metabolism during obesity, ob/ob mice were treated for 5 weeks with the synthetic LXR agonist GW3965. MRI analysis revealed that pharmacological activation of LXR modified fat distribution by decreasing visceral (VS) fat and inverse...

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Detalhes bibliográficos
Main Authors: Archer, Amena, Stolarczyk, Émilie, Doria, Maria Luisa, Helguero, Luisa, Domingues, Rosário, Howard, Jane K., Mode, Agneta, Korach-André, Marion, Gustafsson, Jan-Åke
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622325/
https://ncbi.nlm.nih.gov/pubmed/23446231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M033977
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