Continuous infusion of the cannabinoid WIN 55,212–2 to the site of a peripheral nerve injury reduces mechanical and cold hypersensitivity

BACKGROUND AND PURPOSE: Cannabinoids have analgesic and anti-inflammatory properties but their use is limited by psychotropic activity at CNS receptors. Restricting cannabinoid delivery to peripheral tissues at systemically inactive doses offers a potential solution to this problem. EXPERIMENTAL APP...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lever, I J, Pheby, T M, Rice, A S C
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2007
Pynciau:
Research Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013951/
https://ncbi.nlm.nih.gov/pubmed/17375083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707210
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