Continuous infusion of the cannabinoid WIN 55,212–2 to the site of a peripheral nerve injury reduces mechanical and cold hypersensitivity

BACKGROUND AND PURPOSE: Cannabinoids have analgesic and anti-inflammatory properties but their use is limited by psychotropic activity at CNS receptors. Restricting cannabinoid delivery to peripheral tissues at systemically inactive doses offers a potential solution to this problem. EXPERIMENTAL APP...

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Hlavní autoři: Lever, I J, Pheby, T M, Rice, A S C
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2007
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013951/
https://ncbi.nlm.nih.gov/pubmed/17375083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707210
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