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Comparative studies of AJG049, a novel Ca(2+) channel antagonist, on voltage-dependent L-type Ca(2+) currents in intestinal and vascular smooth muscle

BACKGROUND AND PURPOSE: Antagonists of Ca(2+) channels reduce contraction of intestinal smooth muscle but also affect vascular smooth muscle. We have therefore examined the effects of AJG049, a newly synthesized antagonist for regulation of gut motility, on voltage-dependent L-type Ca(2+) channels,...

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Hlavní autoři: Hashimoto, M, Teramoto, N, Zhu, H-L, Takahashi, K, Ito, Y
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013798/
https://ncbi.nlm.nih.gov/pubmed/16921392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706861
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