Rapamycin induces regression of endometriotic lesions by inhibiting neovascularization and cell proliferation

BACKGROUND AND PURPOSE: Rapamycin is a widely used drug with antifungal, immunosuppressant and antiangiogenic effects. Herein, we studied whether immunosuppressive doses of rapamycin are capable of influencing endometriotic lesions. EXPERIMENTAL APPROACH: We tested in vitro the potential of rapamyci...

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Bibliografiske detaljer
Main Authors: Laschke, M W, Elitzsch, A, Scheuer, C, Holstein, J H, Vollmar, B, Menger, M D
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2006
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013796/
https://ncbi.nlm.nih.gov/pubmed/16894343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706857
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