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Kinase-dependent, retinoic acid receptor-independent up-regulation of cyclooxygenase-2 by all-trans retinoic acid in human mesangial cells
BACKGROUND AND PURPOSE: Preliminary results in human mesangial cells (MC) suggested that all-trans retinoic acid (ATRA) increased the expression of COX-2 and the production of prostaglandin E(2) (PGE(2)), a PG with anti-inflammatory effects in MC. The aim of this work is to confirm that ATRA increas...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2013793/ https://ncbi.nlm.nih.gov/pubmed/16894348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706842 |
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