Homeostatic Mechanisms for Iron Storage Revealed by Genetic Manipulations and Live Imaging of Drosophila Ferritin

Ferritin is a symmetric, 24-subunit iron-storage complex assembled of H and L chains. It is found in bacteria, plants, and animals and in two classes of mutations in the human L-chain gene, resulting in hereditary hyperferritinemia cataract syndrome or in neuroferritinopathy. Here, we examined syste...

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Autori principali: Missirlis, Fanis, Kosmidis, Stylianos, Brody, Tom, Mavrakis, Manos, Holmberg, Sara, Odenwald, Ward F., Skoulakis, Efthimios M. C., Rouault, Tracey A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright © 2007 by the Genetics Society of America 2007
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Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013694/
https://ncbi.nlm.nih.gov/pubmed/17603097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.075150
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