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The quinone reductase gene: A unique estrogen receptor-regulated gene that is activated by antiestrogens

Antiestrogens are thought to exert most of their beneficial effects in breast cancer by antagonizing the actions of estrogen. We report here that antiestrogens also stimulate the expression of quinone reductase (QR) [NAD(P)H:quinone oxidoreductase, EC 1.6.99.2], which may provide protective effects...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Montano, Monica M., Katzenellenbogen, Benita S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1997
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20131/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9122238/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.6.2581
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