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Role of Klebsiella pneumoniae OmpK35 Porin in Antimicrobial Resistance

OmpK35 from Klebsiella pneumoniae is the homologue of Escherichia coli OmpF porin. Expression of OmpK35 in K. pneumoniae strain CSUB10R (lacking both OmpK35 and OmpK36) decreased the MICs of cephalosporins and meropenem ≥128-fold and decreased the MICs of imipenem, ciprofloxacin, and chloramphenicol...

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Bibliografiske detaljer
Main Authors: Doménech-Sánchez, Antonio, Martínez-Martínez, Luis, Hernández-Allés, Santiago, del Carmen Conejo, María, Pascual, Álvaro, Tomás, Juan M., Albertí, Sebastián, Benedí, Vicente Javier
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC201126/
https://ncbi.nlm.nih.gov/pubmed/14506051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.10.3332-3335.2003
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