Role of Klebsiella pneumoniae OmpK35 Porin in Antimicrobial Resistance

OmpK35 from Klebsiella pneumoniae is the homologue of Escherichia coli OmpF porin. Expression of OmpK35 in K. pneumoniae strain CSUB10R (lacking both OmpK35 and OmpK36) decreased the MICs of cephalosporins and meropenem ≥128-fold and decreased the MICs of imipenem, ciprofloxacin, and chloramphenicol...

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Main Authors: Doménech-Sánchez, Antonio, Martínez-Martínez, Luis, Hernández-Allés, Santiago, del Carmen Conejo, María, Pascual, Álvaro, Tomás, Juan M., Albertí, Sebastián, Benedí, Vicente Javier
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Mechanisms of Resistance
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC201126/
https://ncbi.nlm.nih.gov/pubmed/14506051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.10.3332-3335.2003
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