Isophosphoramide mustard, a metabolite of ifosfamide with activity against murine tumours comparable to cyclophosphamide.

Isophosphoramide mustard was synthesized and was found to demonstrate activity essentially comparable to cyclophosphamide and ifosfamide against L1210 and P388 leukaemia. Lewis lung carcinoma, mammary adenocarcinoma 16/C, ovarian sarcoma M5076, and colon tumour 6A, in mice and Yoshida ascitic sarcom...

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Главные авторы: Struck, R. F., Dykes, D. J., Corbett, T. H., Suling, W. J., Trader, M. W.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 1983
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2011256/
https://ncbi.nlm.nih.gov/pubmed/6821629
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