PCR and Restriction Endonuclease Assay for Detection of a Novel Mutation Associated with Sulfonamide Resistance in Neisseria meningitidis

We identified a previously undocumented mutation in the dihydropteroate synthase (folP) gene associated with Neisseria meningitidis sulfonamide resistance. A PCR-based assay to detect this mutation, which is 100% predictive of sulfonamide resistance, was developed.

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Hlavní autoři: Bennett, Désirée E., Cafferkey, Mary T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC201121/
https://ncbi.nlm.nih.gov/pubmed/14506052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.10.3336-3338.2003
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