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PCR and Restriction Endonuclease Assay for Detection of a Novel Mutation Associated with Sulfonamide Resistance in Neisseria meningitidis

We identified a previously undocumented mutation in the dihydropteroate synthase (folP) gene associated with Neisseria meningitidis sulfonamide resistance. A PCR-based assay to detect this mutation, which is 100% predictive of sulfonamide resistance, was developed.

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Bennett, Désirée E., Cafferkey, Mary T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC201121/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14506052/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.10.3336-3338.2003
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