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In vivo assessment of basic 2-nitroimidazole radiosensitizers.

The radiosensitizing efficiencies of 4 structural analogues of misonidazole (MISO) have been compared with that of the parent compound. Three of these were charged basic compounds, previously shown in vitro to be 10 times more efficient. Enhancement ratios were measured from pairs of tumour growth-d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Williams, M. V., Denekamp, J., Minchinton, A. I., Stratford, M. R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1982
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2011061/
https://ncbi.nlm.nih.gov/pubmed/7104192
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