Parenchymal Organ, and Not Splenic, Immunity Correlates with Host Survival during Disseminated Candidiasis

We examined the relationship between host survival and renal and splenic immune responses in a murine model of hematogenously disseminated candidiasis. Male BALB/c mice were infected via tail vein injection with wild-type C. albicans or with an isogenic, Δefg1/Δefg1 hypha-deficient mutant. Host surv...

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Main Authors: Spellberg, Brad, Johnston, Douglas, Phan, Quynh Trang, Edwards, John E., French, Samuel W., Ibrahim, Ashraf S., Filler, Scott G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Fungal and Parasitic Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC201094/
https://ncbi.nlm.nih.gov/pubmed/14500497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.10.5756-5764.2003
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