Exploring the basis of peptide–carbohydrate crossreactivity: Evidence for discrimination by peptides between closely related anti-carbohydrate antibodies

To investigate the molecular basis of antigenic mimicry by peptides, we studied a panel of closely related mAbs directed against the cell-wall polysaccharide of group A Streptococcus. These antibodies have restricted V-gene usage, indicating a shared mechanism of binding to a single epitope. Epitope...

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Detalhes bibliográficos
Main Authors: Harris, Shannon L., Craig, Lisa, Mehroke, Jarnail S., Rashed, Michael, Zwick, Michael B., Kenar, Kelly, Toone, Eric J., Greenspan, Neil, Auzanneau, France-Isabelle, Marino-Albernas, José-R., Pinto, B. Mario, Scott, Jamie K.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20109/
https://ncbi.nlm.nih.gov/pubmed/9122216
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