Brucella Lumazine Synthase Elicits a Mixed Th1-Th2 Immune Response and Reduces Infection in Mice Challenged with Brucella abortus 544 Independently of the Adjuvant Formulation Used

The immunogenicity and protective efficacy of recombinant lumazine synthase from Brucella spp. (rBLS) administered with different adjuvants was evaluated in mice. Mice were immunized with rBLS in the absence or the presence of aluminum hydroxide gel (BLS-Al), monophosphoryl lipid A (BLS-MPA), or inc...

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Detalhes bibliográficos
Main Authors: Velikovsky, Carlos A., Goldbaum, Fernando A., Cassataro, Juliana, Estein, Silvia, Bowden, Raúl A., Bruno, Laura, Fossati, Carlos A., Giambartolomei, Guillermo H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC201088/
https://ncbi.nlm.nih.gov/pubmed/14500496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.10.5750-5755.2003
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