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Brucella Lumazine Synthase Elicits a Mixed Th1-Th2 Immune Response and Reduces Infection in Mice Challenged with Brucella abortus 544 Independently of the Adjuvant Formulation Used

The immunogenicity and protective efficacy of recombinant lumazine synthase from Brucella spp. (rBLS) administered with different adjuvants was evaluated in mice. Mice were immunized with rBLS in the absence or the presence of aluminum hydroxide gel (BLS-Al), monophosphoryl lipid A (BLS-MPA), or inc...

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Библиографические подробности
Опубликовано в::Infect Immun
Главные авторы: Velikovsky, Carlos A., Goldbaum, Fernando A., Cassataro, Juliana, Estein, Silvia, Bowden, Raúl A., Bruno, Laura, Fossati, Carlos A., Giambartolomei, Guillermo H.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2003
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC201088/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14500496/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.10.5750-5755.2003
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