Construction and Functional Activities of Chimeric Mouse-Human Immunoglobulin G and Immunoglobulin M Antibodies against the Neisseria meningitidis PorA P1.7 and P1.16 Epitopes

We studied the in vitro protective activities of human immunoglobulin G1 (IgG1), IgG3, and IgM antibodies against group B meningococci by constructing sets of chimeric mouse-human antibodies (chIgG1, chIgG3, and chIgM, respectively) with identical binding regions against the P1.7 and P1.16 epitopes...

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Pubblicato in:	Infect Immun
Autori principali:	Michaelsen, Terje E., Ihle, Øistein, Beckstrøm, Karen Johanne, Herstad, Tove K., Kolberg, Jan, Høiby, E. Arne, Aase, Audun
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Microbial Immunity and Vaccines
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC201080/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14500492/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.10.5714-5723.2003
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