Construction and Functional Activities of Chimeric Mouse-Human Immunoglobulin G and Immunoglobulin M Antibodies against the Neisseria meningitidis PorA P1.7 and P1.16 Epitopes

We studied the in vitro protective activities of human immunoglobulin G1 (IgG1), IgG3, and IgM antibodies against group B meningococci by constructing sets of chimeric mouse-human antibodies (chIgG1, chIgG3, and chIgM, respectively) with identical binding regions against the P1.7 and P1.16 epitopes...

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Detalhes bibliográficos
Main Authors: Michaelsen, Terje E., Ihle, Øistein, Beckstrøm, Karen Johanne, Herstad, Tove K., Kolberg, Jan, Høiby, E. Arne, Aase, Audun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC201080/
https://ncbi.nlm.nih.gov/pubmed/14500492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.10.5714-5723.2003
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