Evaluation of the Roles of Four Candida albicans Genes in Virulence by Using Gene Disruption Strains That Express URA3 from the Native Locus

Reintroducing URA3 to its native locus in Candida albicans not5, not3, bur2, and kel1 disruption mutants enabled us to directly compare strains with control strain CAI-12. We showed that URA3 position affected orotidine 5′-monophosphate decarboxylase activity, hyphal morphogenesis, adherence, and mo...

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Bibliographische Detailangaben
Hauptverfasser: Cheng, Shaoji, Nguyen, M. Hong, Zhang, Zongde, Jia, Hongyan, Handfield, Martin, Clancy, Cornelius J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC201070/
https://ncbi.nlm.nih.gov/pubmed/14500538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.10.6101-6103.2003
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