Evaluation of the Roles of Four Candida albicans Genes in Virulence by Using Gene Disruption Strains That Express URA3 from the Native Locus

Reintroducing URA3 to its native locus in Candida albicans not5, not3, bur2, and kel1 disruption mutants enabled us to directly compare strains with control strain CAI-12. We showed that URA3 position affected orotidine 5′-monophosphate decarboxylase activity, hyphal morphogenesis, adherence, and mo...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Cheng, Shaoji, Nguyen, M. Hong, Zhang, Zongde, Jia, Hongyan, Handfield, Martin, Clancy, Cornelius J.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2003
Fag:	Fungal and Parasitic Infections
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC201070/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14500538/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.10.6101-6103.2003
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