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Cytotoxic properties of a 4-nitroimidazole (NSC 38087): a radiosensitizer of hypoxic cells in vitro.

5-Phenoxysulphonyl-1-methyl-4-nitroimidazole (NSC 38087) can act as a sensitizer of hypoxic mammalian cells to radiation in vitro. The degree of sensitization achieved is greater than would be predicted from the drug's electron affinity. Cytotoxicity studies have shown that 5 microM NSC 38087 c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Stratford, I. J., Williamson, C., Hardy, C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1981
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2010648/
https://ncbi.nlm.nih.gov/pubmed/7259957
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