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Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice

The severe combined immune deficiency (SCID) mouse was reported as an animal model for human immune deficiency. Through the course of several studies, the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) gene came to be considered a candidate for the SCID-responsible gene. We isolated an OR...

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Bibliografische gegevens
Hoofdauteurs: Araki, Ryoko, Fujimori, Akira, Hamatani, Kiyohiro, Mita, Kazuei, Saito, Toshiyuki, Mori, Masahiko, Fukumura, Ryutaro, Morimyo, Mitsuoki, Muto, Masahiro, Itoh, Masahiro, Tatsumi, Kouichi, Abe, Masumi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences of the USA 1997
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC20106/
https://ncbi.nlm.nih.gov/pubmed/9122213
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