Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice

The severe combined immune deficiency (SCID) mouse was reported as an animal model for human immune deficiency. Through the course of several studies, the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) gene came to be considered a candidate for the SCID-responsible gene. We isolated an OR...

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Detalhes bibliográficos
Main Authors: Araki, Ryoko, Fujimori, Akira, Hamatani, Kiyohiro, Mita, Kazuei, Saito, Toshiyuki, Mori, Masahiko, Fukumura, Ryutaro, Morimyo, Mitsuoki, Muto, Masahiro, Itoh, Masahiro, Tatsumi, Kouichi, Abe, Masumi
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20106/
https://ncbi.nlm.nih.gov/pubmed/9122213
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