A carregar...
The relationship of physico-chemical properties and structure to the differential antiplasmodial activity of the cinchona alkaloids
BACKGROUND: The 8-amino and 9-hydroxy substituents of antimalarial cinchona alkaloids have the erythro orientation while their inactive 9-epimers are threo. From the X-ray structures a 90° difference in torsion angle between the N1-H1 and C9-O12 bonds in the two series is believed to be important. I...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2003
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC201021/ https://ncbi.nlm.nih.gov/pubmed/14505493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-2-26 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|