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Effects of pretreatment with phenobarbitone and phenytoin on the pharmacokinetics and toxicity of phenytoin on the pharmacokinetics and toxicity of misonidazole in mice.

Concentrations of the hypoxic cell radiosensitizer misonidazole (MIS) and its O-demethylated metabolite Ro 05-9963 were determined in plasma (or blood), brain and tumour after injection of 1 g/kg MIS i.p. to control mice or mice pretreated with 4-6 daily injections of phenobarbitone or phenytoin. An...

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Kaydedildi:
Detaylı Bibliyografya
Yazar: Workman, P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 1979
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2010042/
https://ncbi.nlm.nih.gov/pubmed/508562
Etiketler: Etiketle
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