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The effect of phenytoin, phenobarbitone, dexamethasone and flurbiprofen on misonidazole neurotoxicity in mice.

Using a quantitative cytochemical technique for measuring beta-glucuronidase activity in the peripheral nerves of mice, we have investigated the effectiveness of four potential adjuncts for reducing the dose limiting neurotoxicity of misonidazole (MISO) in the clinic. Under the conditions used, the...

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Autores principales: Sheldon, P. W., Clarke, C., Dawson, K. B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1984
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976702/
https://ncbi.nlm.nih.gov/pubmed/6696821
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