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Effect of lipophilicity of nitroimidazoles on radiosensitization of hypoxic bacterial cells in vitro.

The effect of radiosensitization of hypoxic bacterial cells by 9 nitroimidazoles was measured in the bacterial strains E. coli AB 1157 and S. lactis 712. Seven of these compounds were similar to misonidazole in their redox properties, but differed widely in their lipophilicites. The dependence of se...

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Autori principali: Anderson, R. F., Patel, K. B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1979
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009997/
https://ncbi.nlm.nih.gov/pubmed/109112
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