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Microenvironmental arginine depletion by macrophages in vivo.

Since the tumour-selective cytotoxic activity of activated macrophages in vitro can be attributed to depletion of the culture medium of L-arginine by macrophage arginase, a series of experiments was designed to determine whether such a mechanism could operate in vivo. Extracellular fluid obtained fr...

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Hlavní autoři: Currie, G. A., Gyure, L., Cifuentes, L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1979
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009995/
https://ncbi.nlm.nih.gov/pubmed/444403
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