Marrow autotransplantation accelerates haematological recovery in patients with malignant melanoma treated with high-dose melphalan.

In a Phase I study, melphalan 140 mg/m2 was administered to 8 patients with disseminated malignant melanoma. Marrow was removed from the patients immediately before melphalan administration and returned i.v. 8 h later. Studies on marrow culture and melphalan pharmacokinetics predicted that this was...

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Detalhes bibliográficos
Main Authors: McElwain, T. J., Hedley, D. W., Burton, G., Clink, H. M., Gordon, M. Y., Jarman, M., Juttner, C. A., Millar, J. L., Milsted, R. A., Prentice, G., Smith, I. E., Spence, D., Woods, M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1979
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009972/
https://ncbi.nlm.nih.gov/pubmed/383125
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