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Verapamil potentiation of melphalan cytotoxicity and cellular uptake in murine fibrosarcoma and bone marrow.

Growth delay by melphalan of two fibrosarcomas in CBA mice was prolonged by intraperitoneal (i.p.) verapamil, 10 mg kg-1. Verapamil also increased the area under the blood concentration time curve and the gastrointestinal toxicity of melphalan. Verapamil promoted melphalan cytotoxicity to murine bon...

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Bibliografiske detaljer
Main Authors: Robinson, B. A., Clutterbuck, R. D., Millar, J. L., McElwain, T. J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1985
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977281/
https://ncbi.nlm.nih.gov/pubmed/4074636
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