Laddar...
High-affinity T helper epitope induces complementary helper and APC polarization, increased CTL, and protection against viral infection
Natural viral proteins do not always make optimal vaccines. We have found that sequence modification to increase epitope affinity for class II MHC molecules (epitope enhancement) can improve immunogenicity. Here we show first that a higher-affinity helper epitope-enhanced HIV vaccine not only induce...
Sparad:
| Huvudupphovsmän: | , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Clinical Investigation
2001
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC200990/ https://ncbi.nlm.nih.gov/pubmed/11733563 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|